Latanoprost, sold under the brand name Xalatan among others, is a medication used to treat increased pressure inside the eye. *Reported by ≥2% of patients in either cohort at either time point. There were no serious, unexpected, related adverse events reported for any therapy. Travatan (travoprost) Prescription only. However, once the patent protection expires, other manufacturers can make the medication as a generic and then it is sold under its chemical name. Individual time points were similar between treatments, except at 6 pm when travoprost provided lower IOP (16.7+/-2.6 vs 17.9+/-2.5 mmHg, P<0.001). Lumigan (bimatoprost) is an effective first-line treatment for high eye pressure, but it might cause changes to your eyelashes and eye color. IOP = intraocular pressure. Lumigan . Free E-newsletter Subscribe to Housecall. 2003;20(8):597-630. doi: 10.2165/00002512-200320080-00005. Although we hypothesized that the rate of index therapy change would be lower with travoprost-Z preserved with SofZia than with latanoprost preserved with BAK, we found change rates to be statistically significantly lower in latanoprost-treated patients both within six months and across the full study period. This study evaluated the safety and intraocular pressure-lowering efficacy of two concentrations of travoprost (0.0015% and 0.004%) compared with latanoprost 0.005% and timolol 0.5% in patients with open-angle glaucoma or ocular hypertension. Adjusted (ANCOVA) reductions in mean IOP at 8:00 am were similar (P = .128) as were those at 12 noon, 4:00 pm, and 8:00 pm. Insufficient IOP reduction was the most commonly reported reason for change, but IOP changes at the patient level were not assessed and could be considered in future analyses. Franks WA, Renard JP, Cunliffe IA, Rojanapongpun P. Clin Ther. Xalatan (Latanoprost) lowers high pressure in the eye well and helps prevent glaucoma.

However, it is not practical to measure how much medication is in the patient’s eye after eye drop administration, so other studies are then necessary.There are some stringent requirements that generics must meet. In addition, the mean maximum IOP for travoprost was lower than with latanoprost (P ϭ 0.004).As with the absolute level of IOP, the reduction from baseline was statistically greater with travoprost than with latanoprost at 6 PM (Table 3), for the 24-hour curve and mean maximum pressure (PϽ0.004). Bimatoprost and travoprost produced the most growth with no significant difference between the two groups by t-testing. Clipboard, Search History, and several other advanced features are temporarily unavailable. T2 - Economic evaluation based on visual field deficit progression. Int J Mol Sci. Perry CM, McGavin JK, Culy CR, Ibbotson T. Drugs Aging. Comparison of topical travoprost eye drops given once daily and timolol 0.5% given twice daily in patients with open-angle glaucoma or ocular hypertension. Nevertheless, such contrasting results suggest that additional research is needed to evaluate whether the low levels of BAK contained in ophthalmic solutions may cause significant adverse corneal effects that impact patient persistence.  |  Common side effects include red eyes, blurry vision, eye pain, dry eyes, and change in color of the eyes. Withdrawn patients included one (latanoprost) for lack of efficacy, five (three travoprost, one latanoprost, one DTFC) for adverse events, and two (one latanoprost, one DTFC) for loss of follow-up. However, the follow-up time frame was too short to support assessments of changes in parameters such as visual field. Purpose To compare the effects of travoprost 0.004% and latanoprost 0.005% on the intraocular pressure (IOP) of normal dogs.. Methods Twenty mixed breed dogs were randomized to two groups: latanoprost was used in group A and travoprost in group B. Also like the related drugs, latanoprost acid is an analog of prostaglandin F 2α that acts as a selective agonist at the prostaglandin F receptor. Changes in ocular hypotensive therapy may be precipitated by a number of factors. Conclusions: Travoprost (0.0015% and 0.004%), a highly selective, potent prostaglandin F (FP) receptor agonist, is equal or superior to latanoprost and superior to timolol in lowering intraocular pressure in patients with open-angle glaucoma or ocular hypertension. eHealthMe is studying from 18,717 Latanoprost users now. Please enable it to take advantage of the complete set of features! 2011;11 © 2011 BioMed Central, Ltd. SD = standard deviation. 2006 Mar;28(3):332-9. doi: 10.1016/j.clinthera.2006.03.001. Xalatan (Latanoprost) lowers high pressure in the eye well and helps prevent glaucoma. The study is based on travoprost and latanoprost (the active ingredients of Travatan z and Latanoprost, respectively). Our general interest e-newsletter keeps you up to date on a wide variety of health topics. The main aim of this study HHS Bimatoprost and travoprost produced the most growth with no significant difference between the two groups by t-testing. Methods: Latanoprost dominated (i.e., was more effective and less expen-sive than) bimatoprost and travoprost in Norway and Sweden. Compare the IOP lowering properties of latanoprost, travoprost and bimatoprost Full Title of Study: “A Comparison of Latanoprost (Xalatan) With Travoprost (Travatan) and Bimatoprost (Lumigan) in Patients With Elevated Intraocular Pressure. On November 2, 2017, the FDA approved VYZULTA™ (latanoprostene bunod 0.024%) for the treatment of glaucoma. Travoprost lowers pressure inside the eye by increasing the amount of fluid that drains from the eye. What is Latanoprost? On day 3 of using these drops he is experiencing the following symptoms: tenderness of the eye [feels bruised when touching lid]. To compare the 24-h IOP reductions induced by latanoprost, travoprost, and bimatoprost in eyes with exfoliation syndrome (XFS) associated with ocular hypertension (OH). In the United States, latanoprost has been commercially available since 1996, with bimatoprost, travoprost, and unoprostone receiving Food and Drug Administration (FDA) approval between August 2000 and March 2001.2 Although the precise mechanism used by The first prostaglandin analog available was latanoprost. We set out to compare the IOP ... Like tafluprost and travoprost, latanoprost is an ester prodrug that is activated to the free acid in the cornea. Medicine (Baltimore). When the treatment/IOP interval was >24 hours (n = 461), travoprost was superior to latanoprost, i.e. In addition, time to and reasons for changing medication were not cross-validated by an independent committee and were not evaluated in a masked fashion. latanoprost vs bimatoprost), fewer reported hyperemia (P.001, latanoprost vs bimatoprost), and average hyper- emia scores were lower at week 12 (P.001, latano-prost vs bimatoprost). Menu . Prostaglandin analogue side effects are local and involve hyperemia, increased lash growth, periocular skin pigmentation and increased iris pigmentation [30 c]. Skip to: full site navigation. Travoprost (0.0015% and 0.004%), a highly selective, potent prostaglandin F (FP) receptor agonist, is equal or superior to latanoprost and superior to timolol in lowering intraocular pressure in patients with open-angle glaucoma or ocular hypertension. The Intraocular Pressure-Lowering Effect of Persimmon leaves (. Would you like email updates of new search results? METHODS This randomized, prospective, investigator-masked study has been conducted with 50 PXG patients. Although we did not find lower rates of therapy change among those treated with travoprost-Z, future research might expand the study by comparing persistence with BAK-preserved travoprost, bimatoprost, and latanoprost versus ocular hypotensive formulations without BAK - including travoprost with SofZia. doi: 10.1016/s0039-6257(02)00327-2. You may also notice increased growth or thickness of your eyelashes. 2020 Jun;27(6):1569-1572. doi: 10.1016/j.sjbs.2020.03.013. NCI CPTC Antibody Characterization Program. Dosage of drugs is not considered in the study. This Sections. Travoprost ophthalmic may cause a gradual change in the color of your eyes or eyelids and lashes, usually an increase in brown pigment. A major strength of the current study was the large number of charts reviewed (N = 900). Conclusions: Am J Ophthalmol. Based on the Cox proportional hazards model. doi: 10.1097/MD.0000000000016597. Common Questions and Answers about Travoprost vs travoprost z. travatan. Lowers eye pressure. Surv Ophthalmol. Joel M Fain; Sameer Kotak; Jack Mardekian; Jason Bacharach; Deepak P Edward; Steven Rauchman; Teresa Brevetti; Janet L Fox; Cherie Lovelace. In the process of diagnosing possible glaucoma He has been prescribed Travatan [travoprost opthalmic solution) 0.004% 1 gtts Left Eye per day. It is often used in glaucoma. This website also contains material copyrighted by 3rd parties. Drug: latanoprost 0.005% ophthalmic solution Drug: Travoprost 004% sterile ophthalmic solution Drug: Bimatoprost .03% sterile ophthalmic solution Phase 4 Study Design Histologic Remission Does Not Offer Additional Benefit for Ulcerative Colitis Patients in Endoscopic Remission, Slow Taper off Antimalarial Is Best to Avoid Lupus Flare During Remission, Aspergillosis Complicating Severe Coronavirus Disease. Click the topic below to receive emails when new articles are available. Goldberg I, Cunha-Vaz J, Jakobsen JE, Nordmann JP, Trost E, Sullivan EK; International Travoprost Study Group. Travatan (travoprost) is a first-choice treatment to prevent and treat glaucoma because it's … Konstas AG. Menu . Travoprost, sold under the brand name Travatan among others, is a medication used to treat high pressure inside the eye including glaucoma. The study is based on travoprost and latanoprost (the active ingredients of Travatan z and Latanoprost, respectively). Latanoprost exhibited greater ocular tolerability. Methods: This double‐masked, active‐controlled, parallel‐group, multinational, multicentre, phase III study was conducted at 49 centres in 8 countries. Conclusions Latanoprost, bimatoprost, and travoprost used as monotherapy producedsignificant and equivalent reductions in IOP in glaucomatous monkey eyes.The IOP effects of the commercial concentrations of bimatoprost or travoprostwere additive to that of latanoprost, with bimatoprost showing a greater additiveresponse than travoprost. Based on a criterion of 30% or greater intraocular pressure reduction from diurnal baseline or intraocular pressure 17 mm Hg or less, travoprost 0.0015% and 0.004% had an overall response to treatment of 49.3% and 54.7%, respectively, compared with 49.6% for latanoprost and 39.0% for timolol. eCollection 2019. CONCLUSIONS: All three ophthalmic drugs (bimatoprost, latanoprost, and travoprost) are an effective therapy for increasing eyelash growth. Side Effects. This lack of association between these agents and the incidence of dry eye parallel the results of a retrospective analysis of three large prescription databases that found no significant difference in the incidence of ocular surface disease (defined as dry eye or ocular infection) between patients prescribed latanoprost versus travoprost-Z (14.0% vs 14.4%, respectively; p = 0.45).[37]. Travatan (travoprost) is a first-choice treatment to prevent and treat glaucoma because it's effective and has few side effects. The use of travoprost (Travatan Z’s active drug) and latanoprost in treating increased eye pressure has been directly compared in a 2001 clinical study. Latanoprost : an update of its use in glaucoma and ocular hypertension. Lumigan (active ingredient – bimatoprost) belongs to a class of drugs called prostamides that lower pressure in the eye by increasing the amount of fluid that drains from the eye. Overall, patients using travoprost or bimatoprost had a significantly lower rate of adjunctive medication use compared to patients starting on latanoprost monotherapy (22.5%, 23.2%, and 30.2 %, respectively). Rates of therapy "gaps" and restarts, which have been documented using large medical/pharmacy databases,[10,11] cannot be reliably inferred from medical records. Effects generally occur within two hours. performed a prospective, open label, non-randomized cohort study to compare ocular surface changes in patients using BAK preserved latanoprost vs travoprost preserved with SofZia. 2002 Aug;47 Suppl 1:S105-15. In all, 410 of 411 randomized patients were included in intent-to-treat analyses (latanoprost, 136; bimatoprost, 136; travoprost, 138). Side Effects . Measurements were performed at the initial diagnosis, 6th, 12th, and 24th months. 3North Bay Eye Associates, Petaluma, CA, USA. Common Questions and Answers about Travoprost vs travoprost z. travatan. It has been suggested that BAK exposure is related to an increased incidence of dry eye,[15] but therapy withdrawals from dry eye were not obvious in the latanoprost with BAK group.. *Chi-square test. Purpose: What is Travatan? Keeping Eyes Safe From COVID-19: What Works? Xalatan (Latanoprost) lowers high pressure in the eye well and helps prevent glaucoma. Pandemic Screen Time: Will Blue Light Glasses Help? [41–44] In the GAPS,[44] IOP and results of disc evaluations and imaging and of visual field tests were recorded in charts of 90% of open-angle glaucoma patients; in contrast, chart notations of central corneal thickness measurement, gonioscopy, and establishment of an IOP target level were present for about half of patients. A Twelve-Week, Masked Evaluator, Phase IV, Multicenter Study in the United States. Abstract. Latanoprost Ophthalmic rated 5.3/10 vs … Bimatoprost and travoprost produced the most growth with no significant difference between the two groups by t-testing. ‡p < 0.05. Drug information provided by: IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Latanoprost ophthalmic (brand name – Xalatan) is used to treat glaucoma as well as other causes of high pressure inside the eye. The data were collected prospectively from the patients, who were medicated with bimatoprost or latanoprost, at the initial diagnosis of glaucoma. The American Academy of Ophthalmology[38,39] and the European Glaucoma Society[40] have produced guidelines for the evaluation and treatment of patients with glaucoma or ocular hypertension, but eye care professionals may not routinely follow these recommendations. Please enter a Recipient Address and/or check the Send me a copy checkbox. Travatan (travoprost) is a first-choice treatment to prevent and treat glaucoma because it's effective and has few side effects. Learn about side effects, warnings, and more. Control of IOP during the day by drugs is an important therapeutic target. T1 - Travoprost versus latanoprost combinations in glaucoma. Travoprost 0.004% was more effective than latanoprost and timolol in reducing intraocular pressure in black patients by up to 2.4 mm Hg (versus latanoprost) and 4.6 mm Hg (versus timolol). 1Pfizer Ophthalmics, Chicago, IL, USA. Although not all of these side effects may occur, if they do occur they may need medical attention. In the GAPS,[11] hyperemia also was the most common adverse event. Evaluating Glaucoma Treatment Effect on Intraocular Pressure Reduction Using Propensity Score Weighted Regression. 2003). 2019 Sep 30;13:3453-3463. doi: 10.2147/DDDT.S222796. 4Summa Health System, Akron, OH, USA. glandin analogues latanoprost, bimatoprost, travoprost, and unoprostone. Similar proportions of patients in the two treatment groups changed due to a glaucoma-related surgery or procedure (approximately 14% at each measurement time point). Latanoprost, Bimatoprost, Travoprost, Latanoprostene Bunod General. Compare Travatan vs. Xalatan Head-to-head comparisons of medication uses, side effects, ratings, and more. 2001 Oct;10(5):414-22. doi: 10.1097/00061198-200110000-00010. Travatan has active ingredients of travoprost. Bimatoprost and travoprost: a review of recent studies of two new glaucoma drugs. More than one reason could be reported for each patient. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. The most frequently recorded adverse event was hyperemia, which was noted significantly more frequently with travoprost-Z than with latanoprost at both measurement time points. Eight hundred one patients with open-angle glaucoma or ocular hypertension were randomly assigned to travoprost 0.0015%, travoprost 0.004%, latanoprost 0.005%, or timolol 0.5%. Other procedures and ocular surface tests were performed less frequently. While the “brand name” drug is still on the market, there may be two different names for the same medication. The travoprost/timolol combination may have a slightly longer duration of action than the latanoprost/timolol fixed combination. In addition, travoprost 0.004% is significantly better than either latanoprost or timolol in lowering intraocular pressure in black patients. Links. Ophthalmology. Aggregator Full Text. Skip to: full site navigation. Color changes may be permanent even after your treatment ends, and may occur only in the eye being treated. Results. Addition of timolol to travoprost resulted in an additional IOP reduction similar to that seen when added to latanoprost [3]. In that study, of the 195 patients with charted adverse events, hyperemia was noted in 135 (69%) records, and an episode of hyperemia occurred in a significantly greater proportion of those exposed to travoprost (35%) than to latanoprost (22%; p = 0.0123). J Glaucoma. Latanoprost exhibited greater ocular tolerability. Dosage of drugs is not considered in the study. Background/aims To assess the comparative efficacy of latanoprostene bunod (LBN), a novel prostaglandin analogue (PGA), to other medications for open-angle glaucoma and ocular hypertension on lowering intraocular pressure (IOP). To compare the 24-h IOP reductions induced by latanoprost, travoprost, and bimatoprost in eyes with exfoliation syndrome (XFS) associated with ocular hypertension (OH). more patients using travoprost attained the predefined target IOP (78.5% vs 68.3%; p = 0.0344), and the mean IOP value was lower in the travoprost group (16.8 vs 17.8mm Hg; p = 0.0016). generic drugs or brand names) are also considered. CONCLUSIONS: All three ophthalmic drugs (bimatoprost, latanoprost, and travoprost) are an effective therapy for increasing eyelash growth. Efficacy and safety of prostaglandin analogues in primary open-angle glaucoma or ocular hypertension patients: A meta-analysis. It is often used in glaucoma. It is used as an eye drop. Methods A … In Denmark, bimatoprost dominated travoprost. Latanoprost (Ophthalmic Route) Print. The average ocular hyperemia score was less than 1 on a scale of 0 to 3, indicating that on average patients experienced between none/trace and mild for all treatment groups. Orzalesi N, Rossetti L, Bottoli A, Fogagnolo P: Comparison of the effects of latanoprost, travoprost, and bimatoprost on circadian intraocular pressure in patients with glaucoma or ocular hypertension. Publisher Full Text. Prostaglandins increase the sclera's permeability to … Results: A synthetic analogue of prostaglandin F2alpha, ophthalmic solutions of travoprost are used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. Therefore, for every 14 patients treated with latanoprost instead of travoprost or bimatoprost, one additional patient would be expected to need adjunctive therapy with another agent. Kozobolis VP. §Latanoprost, N = 629; travoprost-X, N = 267. Please confirm that you would like to log out of Medscape. Conclusions Latanoprost, bimatoprost, and travoprost used as monotherapy producedsignificant and equivalent reductions in IOP in glaucomatous monkey eyes.The IOP effects of the commercial concentrations of bimatoprost or travoprostwere additive to that of latanoprost, with bimatoprost showing a greater additiveresponse than travoprost. Finally, because latanoprost and the original formulation of travoprost with BAK have similar tolerability profiles,[32,33] we hypothesized that any improvement in the tolerability of travoprost with SofZia would lead to lower rates of therapy change in comparison to latanoprost with BAK. Travoprost compared with latanoprost and timolol in patients with open-angle glaucoma or ocular hypertension.  |  Anti-glaucoma latanoprost-loaded ocular implants provide prolonged delivery and enhanced bioavailability relative to the conventional eye drops. 2Pfizer Ophthalmics, New York, NY, USA. Ahn HR, Yang JW, Kim JY, Lee CY, Kim TJ, Jung SH. Baseline mean 8:00 am IOP levels were similar (P = .772); by week 12, reductions were observed in all 3 groups (P < .001 for each). Burnout Might Really Be Depression; How Do Doctors Cope? There were no significant differences in mean age or gender between the three study groups with the exception that latanoprost patients were statistically older than travoprost patients (69.0 vs. 68.0). NIH generic drugs or brand names) are also considered. Compare Xalatan vs. Travatan Head-to-head comparisons of medication uses, side effects, ratings, and more. Each of the three drugs considerably reduced the IOP in PXG cases throughout the 6 months. This was not considered a clinically meaningful difference. Latanoprost (Xalatan) is an ophthalmic solution used to treat open-angle glaucoma and ocular hypertension. Compare Latanoprost Ophthalmic vs Xalatan head-to-head with other drugs for uses, ratings, cost, side effects and interactions. Saudi J Biol Sci. Latanoprost is one medication within the class of prostaglandin analogs (PGA) approved for such use. SD = standard deviation. †The reference cohort is latanoprost. Compared with the most widely used PGAs, LBN numerically outperformed latanoprost and travoprost and was similar to bimatoprost 0.01%. Travoprost, sold under the brand name Travatan among others, is a medication used to treat high pressure inside the eye including glaucoma. It is the brand name of a drug called bimatoprost (available as an eye-drop), a type of drug which is part of a family of … *Reported by ≥2% of patients in either cohort at either time point. 2002 May;133(5):732; author reply 732-3. doi: 10.1016/s0002-9394(02)01396-x. For example, Cosopt® is the brand name for a combination medicatio… Epub 2020 Mar 16. An IOP measurement was recorded for nearly all (>98%) patients in both treatment groups and about half of charts included findings of perimetry, ophthalmoscopy, gonioscopy, and central corneal thickness measurement. Lowers eye pressure and controls glaucoma. One of these methods of protecting the optic nerve has already been available to those with glaucoma who use prostaglandin analogs such as Xalatan® (latanoprost), Lumigan® (bimatoprost), Travatan-Z® (travoprost … Wu M, Liu M, Schuman JS, Wang Y, Lucy KA, Ishikawa H, Wollstein G. Sci Rep. 2019 Oct 29;9(1):15496. doi: 10.1038/s41598-019-52052-5. †p < 0.05. Adverse events showed more conjunctival hyperemia with travoprost (n = 15) than latanoprost (n = 6; P = 0.03). Description and Brand Names; Before Using; Proper Use; Precautions; Side Effects; Products and services. When the treatment/IOP interval was >24 hours (n = 461), travoprost was superior to latanoprost, i.e. All material on this website is protected by copyright, Copyright © 1994-2021 by WebMD LLC. Combining proportions of patients who either switched or discontinued to estimate how many patients completely stopped taking the initial therapy revealed that, within the first six months, 12.5% (79/632) of latanoprost-treated patients and 15.3% (41/268) of those treated with travoprost-Z stopped the initial therapy and that 19.8% (125/632) and 23.5% (63/268), respectively, did so across the full study period. In particular, the studies by Schmier et al[34–36] included only newly initiating patients who remained on the index prostaglandin for least 12 or 24 months (depending on the study), while the present research identified patients newly prescribed an ocular prostaglandin and tracked therapy changes throughout the follow-up period. * Correspondence Latanoprost has active ingredients of latanoprost. This newly available medication treats glaucoma in two distinct ways. Participants in group 1 were naïve to glaucoma treatment ( n = 28) and those in group to were previously treated with latanoprost. Le latanoprost doit être utilisé avec précautions chez les patients aphaques, chez les patients pseudophaques présentant une rupture capsulaire postérieure ou porteurs d'implant en chambre antérieure ainsi que chez les patients ayant des facteurs de risque connus d'oedème maculaire cystoïde. AU - Schmier, Jordana K. AU - Halpern, Michael T. AU - Covert, David W. AU - Robin, Alan L. PY - 2006/9/1. Travoprost was equal or superior to latanoprost and superior to timolol with mean intraocular pressure over visits and time of day ranging from 17.9 to 19.1 mm Hg (travoprost 0.0015%), 17.7 to 19.1 mm Hg (travoprost 0.004%), 18.5 to 19.2 mm Hg (latanoprost), and 19.4 to 20.3 mm Hg (timolol). Authors +Show Affiliations. Latanoprost, bimatoprost, and travoprost were comparable in their ability to reduce IOP in OAG and OH patients. This site needs JavaScript to work properly. [email protected]zer.com. Drug Des Devel Ther. *N (%) unless otherwise indicated. In the present study, we tabulated frequencies of ocular procedures and ocular surface tests performed at baseline. This was certainly the case with latanoprost, where compatibility with the bottle material was a large part of the research and development process when bringing Xalatan to market. Lumigan vs Latanoprost – Uses, Dosage, Side Effects, Differences. Every effort was made to ensure the consistency of chart abstraction across sites, but no formal tests of reliability were undertaken. 5North Valley Eye, Mission Hills, CA, USA PURPOSE To compare the intraocular pressure (IOP) lowering effect and safety of latanoprost, travoprost given every evening, and the fixed combination dorzolamide + timolol (DTFC) given twice daily in pseudoexfoliation glaucoma (PXG). The efficacy and safety of travoprost (0.0015% and 0.004%) daily was compared with latanoprost daily and timolol twice daily for a period of 12 months. Our finding of greater persistence with latanoprost monotherapy than with travoprost-Z monotherapy contrasts with results of retrospective claims database analyses of prostaglandin analog treatment patterns. Travoprost is the isopropyl ester of prostaglandin F2alpha in which the pentyl group is replaced by a 3-(trifluoromethyl)phenoxymethyl group. How to use the study? As in the GAPS,[11] adverse events were the second most frequently cited reason for change, noted in between 11% and 21% of cases; changes were attributed to adverse events in somewhat greater proportions of those treated with travoprost-Z. Neuro-Ophthalmic Manifestations of Coronavirus Disease 19. More than one event could be reported for each patient. Effect of latanoprost on intraocular pressure, visual acuity and C-reactive protein.

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